Octanoate metabolism in isolated hepatocytes and mitochondria from fetal, newborn and adult rabbit. Evidence for a high capacity for octanoate esterification in term fetal liver
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چکیده
منابع مشابه
passivity in waiting for godot and endgame: a psychoanalytic reading
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Octanoate and palmitate as substrates for ketogenesis by hepatocytes isolated from suckling rabbits.
The lactating rabbit synthesizes milk triacylglycerol, which contains a high proportion (approx. 65 mo1/100mol) of medium-chain fatty acids, the remainder being long-chain fatty acids (Smith et al., 1968). Experiments in vivo with suckling rabbits had shown that medium-chain milk fatty acids were transported to the liver via the hepatic portal vein, and were taken up by the liver. In order to c...
متن کاملMetabolic fate of non-esterified fatty acids in isolated hepatocytes from newborn and young pigs. Evidence for a limited capacity for oxidation and increased capacity for esterification.
In hepatocytes isolated from 48 h-old starved of suckling newborn pigs or from 15-day-old starved piglets, the rate of ketogenesis from oleate or from octanoate is very low. This is not due to an inappropriate fatty acid uptake by the isolated liver cells, but results from a limited capacity for fatty acid oxidation. Some 80-95% of oleate taken up is converted into esterified fats, whatever the...
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ژورنال
عنوان ژورنال: European Journal of Biochemistry
سال: 1989
ISSN: 0014-2956,1432-1033
DOI: 10.1111/j.1432-1033.1989.tb15067.x